Relative efficacy and safety of early lactate clearance-guided therapy resuscitation in patients with sepsis
نویسندگان
چکیده
منابع مشابه
Lactate Levels Can Guide Early Resuscitation Goals in Severe Sepsis Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy: A Randomized Clinical Trial
Background: The Surviving Sepsis Campaign international consensus guidelines recommend early resuscitation to optimize oxygen delivery. Although the best measure of oxygen delivery is debated, the published protocol utilized central venous oxygen saturation (ScvO2) of >70%. Serum lactate has been shown to prognosticate outcome, with higher levels being associated with worse morbidity and mortal...
متن کاملMulticenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis.
We sought to determine (a) if early lactate clearance is associated with improved survival in emergency department patients with severe sepsis and (b) the concordance between central venous oxygen saturation (ScvO2) optimization and lactate clearance during early sepsis resuscitation. Within a multicenter shock research network that uses quantitative resuscitation for severe sepsis, we analyzed...
متن کاملLactate is THE target for early resuscitation in sepsis
The resuscitation of patients in sepsis is a challenge for many reasons. One of the important questions is: Who needs what kind of resuscitation? In the present guidelines, resuscitation is mostly directed at patients with a high risk of mortality. In this review, I will discuss the value of using lactate levels to identify patients who might benefit from treatment and how to use sequential lac...
متن کاملCorrection: Prognostic Value of Lactate and Central Venous Oxygen Saturation after Early Resuscitation in Sepsis Patients
[This corrects the article DOI: 10.1371/journal.pone.0153305.].
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ژورنال
عنوان ژورنال: Medicine
سال: 2019
ISSN: 0025-7974,1536-5964
DOI: 10.1097/md.0000000000014453